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Weed Killers & Preventers

Keep weeds under control with our selection of powerful weed killers and preventers.

Areas of Use

Grass invested with clover.


The best time to apply weed killer and preventer is in the spring or summer, before weeds germinate. Be sure the label says lawn care to prevent damage to your lawn.
A brick paver patio with weeds growing between the cracks.

Driveway, Patio or Sidewalk

Use both a pre- and a post-emergent weed killer to get rid of the weeds that are already there and keep them from growing back.
A person wearing red gardening gloves using a gardening tool to tend to plants.


Pre-emergent and selective weed killers work best and should be applied in the spring, before weeds germinate.

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Prevent and Kill Weeds With Help From Lowe’s

If you’ve found yourself Googling “What kills kudzu naturally?” or “Will vinegar kill poison sumac?” it’s time for a trip to Lowe’s. We offer a full suite of products for weed prevention, as well as weed killers to help you create and maintain a flawless lawn.

Stop Weeds Before They Begin

Spring is the best time to treat your lawn with pre-emergent, as this type of herbicide stops germination and inhibits growth. Pre-emergent herbicides, like crabgrass killer, come in liquid and granule form from the names you know and trust.

Weed Killer for Lawns

Once your lawn establishes, maintenance should be your focus. Inspect and remove grass weeds manually, or use a product like Roundup Weed Killer or Weed B Gon to help target unwanted guests from the lawn and surrounding areas. Just be careful not to overdo it. You can kill grass with these products too.

Natural Weed Killers

Eco-conscious gardeners are sure to appreciate our array of products designed to kill weeds naturally and effectively. After all, it pays to be cautious and considerate of your family when looking for a child- and pet-safe weed killer.

If you find that you’re caught between two products, don’t worry. The best weed killer is the one you’ll actually use. Determine if you’re more likely to use a spreader or a sprayer and buy accordingly. You can always change your application method later if you find your preferences change.

Once your weeds are under control, maintain rich color and robust growth with a liquid lawn fertilizer. We have options both in store and online to make research and buying easy. If you prefer a no-contact option, choose curbside pickup when buying online. A store associate will bring your order to your car.

With Lowe’s, you’ll find affordably priced products and plenty of guidance to build and maintain a weed-free lawn and garden. Explore the Ideas tab at the top of the page to see articles that help you control weeds and crabgrass.